East Africa’s agriculture sector is increasingly vulnerable to the effects of climate change, challenging farmer livelihoods and regional food security. Climate Smart Agriculture’s (CSA) integrated approach will be critical to address this challenge by promoting increased agricultural productivity, resilience, and climate change mitigation. CSA encompasses a wide array of practices, technologies, and approaches, necessitating the participation of a diverse range of stakeholders spanning the public, private and development spheres. Strengthening synergies between public agencies, development partners and private enterprises to address the challenge of agricultural productivity and food security in the region calls for the establishment of an enabling regulatory environment. This Policy Brief provides a general overview of the CSA landscape in East Africa, focusing on the enabling environment, to define a set of policy recommendations.