As Iran commemorates the 40th anniversary of the Islamic Revolution, the West looks at the country with concern. While the regime’s stability remains uncertain under financial and political constraints, Iran’s regional policy displays an aggressive expansionism that contributes to further inflaming an incendiary Middle East. The European Union’s continued course of engagement following the United States' unilateral withdrawal from the Joint and Comprehensive Plan of Action has borne fruit in keeping Iran within the provisions of the nuclear agreement. But neither EU nor U.S. approaches have provided any workable solutions to contain Iran’s aggressive regional ambitions, as shown by its missile program, its threats against Israel, its support to Hizbullah, the Houthis and other proxy militia, and its increasing entrenchment in Syria. The panel will review the linkages between Iran’s domestic dynamics and regional ambitions, and outline possible ways forward for the EU and the United States.